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From209US$ /night
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

700 West Main Street, Louisville, Kentucky, United States, 40202
-
Steps from the Ohio River
Great
8.7
9.3
/10
4.7
4.6
/5

Rooms & Suites

21c Museum Hotel Louisville offers 91 rooms with original artwork, including Atrium Suites with king-sized beds, living and dining areas, and tubs with walk-in showers. The Corner Suite features four large windows overlooking 7th Street, Main Street, and the Ohio River. The Asleep in the Cyclone suite is an immersive artist-designed space with a king-sized platform bed, a record player, and custom linens. All rooms include a Bryte Restorative Sleep Bed, 50-55' HDTVs, Lavazza coffee, and Malin+Goetz bath amenities.

Dining at Proof

Proof on Main serves Southern and Appalachian-inspired cuisine, led by Kentucky native Chef Cody Stone. The lounge houses the 21c Selects Private Barrel Program, featuring regional bourbons. The Fork & Bottle dinner series highlights guest distillers, while the Hog & Barrel dinner includes Pappy Van Winkle tastings.

Art & Events

The hotel includes over 9,000 square feet of exhibition space with rotating contemporary art installations like Fragile Figures: Beings and Time and Tredici Cavalli [13 Horses], made entirely of duct tape. Events include dance performances inspired by the art, curated dinners, and weddings in gallery spaces. The museum is open 24/7 and free to the public.

Downtown Location

The hotel is on Main Street, a half-mile from the Kentucky Museum of Art & Craft, Frazier History Museum, and Muhammad Ali Center. The free ZeroBus stops two blocks away, connecting to Whiskey Row, Slugger Field, and other downtown sites. Old Forester Distillery, known as 'the first bottled bourbon,' is nearby.

Services & Amenities

Guests can book deep tissue or sports massages, use the 24-hour fitness center, or relax in the sauna and steam room. Event planners offer eco-conscious meeting options, and catering menus are tailored to group needs. Valet parking is available, and pet-friendly rooms are offered.

Must-do experiences

  • Stroll through the Big Four Bridge for stunning river views.
  • Savor a Hot Brown at the Brown Hotel, a local culinary classic.
  • Visit the Muhammad Ali Center for inspiring exhibits on the legend.
  • Explore the NuLu district for unique shops and delicious eateries.
  • Catch a live performance at the historic Louisville Palace theatre.
View all

Choose the Room

From cosy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.
Room Balcony
2 persons
29 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner Suite
2 persons
61 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
46 m² 
1 King-size bed
Shower
Coffee machine
Click button to see more rooms
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Check Dates & Room Rates

See what's available for your travel dates

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
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Dining Onsite

At 21C Museum Hotel Louisville, dining transcends the ordinary with a modern American restaurant that brings local flavors to life. Enjoy culinary events that celebrate regional distillers, inviting guests to explore a world where art and cuisine beautifully intertwine.
21C Museum Hotel Louisville Restaurant photo
21C Museum Hotel Louisville Restaurant photo
21C Museum Hotel Louisville Restaurant photo

Proof on Main

Modern American
Ambiance
Sleek and contemporary, featuring artistic decor that reflects the vibrant culture of Louisville.
Key Offerings
A carefully curated menu showcasing seasonal dishes and an impressive selection of spirits, highlighted by special events like the Fork & Bottle dinner series and the Hog & Barrel dinner featuring Pappy Van Winkle.
Reservation
Recommended.
Hours vary; primarily open for dinner.

Location

700 West Main Street, Louisville, Kentucky, United States, 40202
Map view
700 West Main Street, Louisville, Kentucky, United States, 40202
Nearby
Museum
Louisville Slugger Museum & Bat Factory
180 m
Museum
Muhammad Ali Center
280 m
Museum
Kentucky Science Center
140 m
Museum
The Frazier History Museum
260 m
Museum
Kentucky Museum of Art and Craft
70 m
528 W Main St
Evan Williams Bourbon Experience
200 m
Gallery
Flame Run Glass Studio and Gallery
300 m
500 W Main St
The Belvedere
250 m
Night club
Jimmy Can't Dance
90 m
801 W Main St
Michter's Fort Nelson Distillery
150 m
Library
Sons of the American Revolution Genealogical Research Library
190 m
120 N 10th St
Kentucky Peerless Distilling Co
480 m
401 W River Rd
Belle of Louisville Riverboats
580 m
Restaurants
Proof On Main
10 m
702 West Main Street
Mussel & Burger Bar Downtown
60 m
113 S 7th St Located in Louisville's Central Business District
Bristol Bar & Grille
110 m
614 W Main St
Atlantic No. 5
160 m
605 W Main St Located in Louisville's Central Business District.
Los Aztecas Mexican Restaurant
180 m
445 E Market St
Vincenzo's Italian Restaurant
430 m
150 S 5th St
Jockey Silks Bourbon Bar
480 m
140 N 4th St 2nd Floor - West Tower
Dish on Market
470 m
434 W Market St
Quiznos
540 m
223 S 5th St
Swizzle Dinner & Drinks
530 m
140 N Fourth St 25th Floor
Cafe Magnolia
590 m
140 N 4th St Galt House Hotel
Explore Louisville
Explore Louisville
Top Attractions
Activities
Dining
Entertainment
Kentucky Science Center
Kentucky Science Center
2 minutes walking
Interactive exhibits and IMAX films make this science center ideal for families and curious minds of all ages.
Muhammad Ali Center
Muhammad Ali Center
4 minutes walking
A cultural and educational center dedicated to the life and legacy of the boxing legend with inspiring exhibits.
Louisville Slugger Museum & Bat Factory
Louisville Slugger Museum & Bat Factory
3 minutes walking
Home of the iconic baseball bats, this museum showcases baseball history and offers bat-making tours.
Waterfront Park
Waterfront Park
17 minutes walking
A scenic space with walking trails, playgrounds, and open green areas perfect for a leisurely stroll or picnic.
Angel's Envy Distillery
Angel's Envy Distillery
19 minutes walking
This distillery offers tours and tastings for bourbon enthusiasts, showcasing the distillation process and tastings.
Proof On Main
Proof On Main
1 minute walking
Farm-to-table dining with a focus on local ingredients, ideal for enjoying fine dishes and craft cocktails.
Mussel & Burger Bar Downtown
Mussel & Burger Bar Downtown
1 minute walking
Casual eatery specializing in gourmet burgers and mussels, featuring a lively atmosphere great for all diners.
KFC Yum Center
KFC Yum Center
9 minutes walking
A premier venue for concerts and sporting events, known for its vibrant atmosphere and exciting shows.
Fourth Street Live!
10 minutes walking
An energetic entertainment district with live music, restaurants, and bars, perfect for nightlife and gatherings.
Getting around
City Centre
Louisville23 min  ·  1.9 km
Airports
Louisville International Airport (SDF)18 min  ·  11.9 km
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Children & extra beds
Maximum capacity of extra beds in a room is 1. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of floors:
4
Number of rooms:
96
Former name
21c Museum Hotel
Questions of the users
About 21C Museum Hotel Louisville
Are there any guest rooms that feature a balcony for enjoying the outdoor view?
10 January 2024
The Luxury King rooms do not include balconies, but there are two balcony suites and one penthouse with a 2000 sq. ft. terrace available for guests.
What is the parking arrangement at the hotel?
15 February 2024
Valet parking is offered at a rate of $32 per night, which provides unlimited access to your vehicle. Alternatively, self-parking can be done on the surrounding streets or in a nearby parking garage.
What are the fees for bringing small dogs during the stay?
20 March 2024
A pet fee of $75 per room applies for guests traveling with small dogs.
Can arrangements be made for group bookings for events like wedding parties?
25 April 2024
For inquiries about room blocks for events such as weddings, contacting the sales team is recommended.
Do balcony rooms offer a scenic view of the river?
30 May 2024
Rooms with balconies face 7th Street rather than the river. However, Corner Suites provide excellent river views without balconies.
Is there a room option available that includes a bathtub for relaxation?
05 June 2024
Yes, each Deluxe Double Room comes with a bathtub to enhance relaxation during your stay.
Are soaking tubs available in any of the guest rooms?
15 July 2024
Soaking tubs are not available; however, standard-size bathtubs can be found in select rooms.
Is there a honeymoon suite or any special packages for couples?
20 August 2024
Couples can enjoy a honeymoon suite experience through the Love Birds Package, which includes a $100 dinner credit at Proof on Main along with sparkling wine and chocolate strawberries delivered to the room.
What rate can be expected for breakfast during the stay?
30 September 2024
Breakfast is served with sit-down service, and when booked as part of a package, guests can apply an $18 credit per person per day towards breakfast options.
Is it possible to request a rollaway bed for additional sleeping space?
10 October 2024
Rollaway beds can be requested, but availability is limited, so contacting the hotel directly when booking is advisable to secure one.
Are there refrigerators available in the rooms for storing personal items?
15 November 2024
Rooms come equipped with stocked minibars, but empty refrigerators are not provided. Guests can call ahead to request a mini-fridge for their room.
What unique experiences does the hotel offer beyond a typical stay?
25 December 2024
The hotel features immersive art installations, a restaurant with a southern culinary focus, and access to a gallery showcasing contemporary art-all within a vibrant downtown location.

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